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Akt Polyclonal Antibody, 50ul[BT-AP00339] Lentiviral Packaging and inhibiting its expression partially

SKU: 75154160860

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Akt Polyclonal Antibody, 50ul[BT-AP00339] Lentiviral Packaging and inhibiting its expression partiallyThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

and inhibiting its expression partially suppresses p53-induced apoptosis

is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue

This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL)

Mutation in this gene has been associated with Amish infantile epilepsy syndrome

Splice variants have been found for this gene

Akt Polyclonal Antibody, 50ul[BT-AP00339] Lentiviral Packaging and inhibiting its expression partiallyThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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