p300 (Acetyl Lys1542) Polyclonal Antibody, 20ul Adeno-associated Virus Packaging Alternative promoter usage and splicing

Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2

RFC3 encodes the 38 kDa subunit

The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer

but their existence has not been verified

on chromosome 22

p300 (Acetyl Lys1542) Polyclonal Antibody, 20ul Adeno-associated Virus Packaging Alternative promoter usage and splicingThis gene encodes the adenovirus E1A associated cellular p300 transcriptional co activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co activator of HIF1A (hypoxia inducible factor 1