MAGE-A5 Polyclonal Antibody, 50ul Human Genome Knockout Libraries The Fc receptor like 5

The Fc receptor like 5 is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains

May play a role in microtubule nucleation by centrosome

Two transcripts that encode the same protein have been identified for this gene

A second ligand| the heditary hemochromatosis protein HFE| competes for binding with transferrin for an overlapping C-terminal binding site

Nuclear receptor ROR-gamma encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors

MAGE-A5 Polyclonal Antibody, 50ul Human Genome Knockout Libraries The Fc receptor like 5MAGEA5 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary