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GCSc-Gamma Polyclonal Antibody, 100ul Multiplex Immunoassays The mu class of enzymes

SKU: 77639846139

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GCSc-Gamma Polyclonal Antibody, 100ul Multiplex Immunoassays The mu class of enzymesGlutamate cysteine ligase, also known as gamma glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. GCLC encodes Glutamate cysteine ligase catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22 p21. Mutations at GCLC have been associated with hemolytic anemia due to

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Description

The mu class of enzymes functions in the detoxification of electrophilic compounds| including carcinogens| therapeutic drugs| environmental toxins and products of oxidative stress| by conjugation with glutathione

Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies

UBQLN3 is specifically expressed in the testis

Growth Hormone Regulated TBC Protein 1 may act as a GTPase-activating protein for Rab family protein(s)

and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues

GCSc-Gamma Polyclonal Antibody, 100ul Multiplex Immunoassays The mu class of enzymesGlutamate cysteine ligase, also known as gamma glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. GCLC encodes Glutamate cysteine ligase catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22 p21. Mutations at GCLC have been associated with hemolytic anemia due to

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