NPC1 Rabbit Polyclonal Antibody, 20ul Plasmid Preparation blocking interaction with the signal

blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum

similarity:Contains 2 fibronectin type-III domains

consists of a homodimer

CdcA3 is involved in ubiquination and degradation of the mitosis-inhibitory kinase Wee 1

the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor

NPC1 Rabbit Polyclonal Antibody, 20ul Plasmid Preparation blocking interaction with the signalThis gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N terminal domain. It is predicted to have a cytoplasmic C terminus 13 transmembrane domains and 3 large loops in the lumen of the endosome the last loop being at the N terminus. This protein transports low density lipoproteins to late endosomal lysosomal compartments