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NTN Polyclonal Antibody, 50ul Metabolic enzymes GPR158 (G Protein-Coupled Receptor 158)

SKU: 77975125231

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NTN Polyclonal Antibody, 50ul Metabolic enzymes GPR158 (G Protein-Coupled Receptor 158)NRTN encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. Neurturin signals through the RET receptor tyrosine kinase and a GPI linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease.

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Description

GPR158 (G Protein-Coupled Receptor 158) is a Protein Coding gene

Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L)

The encoded protein is one of at least four similar proteins that have been found

Specifically binds poly(G) RNA homopolymers in vitro

This protein is also thought to modify lipid metabolism and insulin-regulated gene expression

NTN Polyclonal Antibody, 50ul Metabolic enzymes GPR158 (G Protein-Coupled Receptor 158)NRTN encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. Neurturin signals through the RET receptor tyrosine kinase and a GPI linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease.

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