SLUG Rabbit Polyclonal Antibody, 20ul Gel & Buffers This gene is a susceptibility

This gene is a susceptibility gene for Moyamoya disease| a vascular disorder of intracranial arteries

and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system

HSPH1 is a Protein Coding gene

at least in part

Alternatively spliced transcript variants encoding different isoforms have been described but their biological nature has not been determined

SLUG Rabbit Polyclonal Antibody, 20ul Gel & Buffers This gene is a susceptibilityThis gene encodes a member of the Snail family of C2H2 type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E box motifs and is also likely to repress E cadherin transcription in breast carcinoma. This protein is involved in epithelial mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.