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NTCP2 Rabbit Polyclonal Antibody, 50ul Polyclonal Antibody Preparation This protein kinase is calcium-independent

SKU: 80668989068

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NTCP2 Rabbit Polyclonal Antibody, 50ul Polyclonal Antibody Preparation This protein kinase is calcium-independentThis gene encodes a sodium bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines

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Description

This protein kinase is calcium-independent and phospholipid-dependent

H3F3A contains introns and its mRNA is polyadenylated

This protein may also play a role in inhibiting viral replication

Binds to F-actin but not to RNA

The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates| such as 8-oxo-dGTP| 8-oxo-dATP| 2-hydroxy-dATP| and 2-hydroxy rATP| to monophosphates| thereby preventing misincorporation

NTCP2 Rabbit Polyclonal Antibody, 50ul Polyclonal Antibody Preparation This protein kinase is calcium-independentThis gene encodes a sodium bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines

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