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Caspase-1 Polyclonal Antibody, 100ul[BT-AP01192] Custom Peptide Synthesis in particular during tumorigenesis

SKU: 81788380114

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Caspase-1 Polyclonal Antibody, 100ul[BT-AP01192] Custom Peptide Synthesis in particular during tumorigenesisCASP1 (caspase 1) encodes a protein which is a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. CASP1 was identified by its ability to proteolytically

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Description

in particular during tumorigenesis

Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro)

The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm

This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP)

GO annotations related to this gene include calcium ion binding and phosphoric diester hydrolase activity

Caspase-1 Polyclonal Antibody, 100ul[BT-AP01192] Custom Peptide Synthesis in particular during tumorigenesisCASP1 (caspase 1) encodes a protein which is a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. CASP1 was identified by its ability to proteolytically

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