CD43 Rabbit Polyclonal Antibody, 50ul Peptide Modification It is a predominantly cytoplasmic

It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines

Interactions have been observed with Bcl-2

with no expression found in 80% of tumor cell lines

an iron overloading disorder predominant in Caucasians

The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal| followed by two fibronectin type-III motifs

CD43 Rabbit Polyclonal Antibody, 50ul Peptide Modification It is a predominantly cytoplasmicThe protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes T lymphocytes monocytes granulocytes and some B lymphocytes. It may be part of a physiologic ligand receptor complex involved in T cell activation. During T cell activation this protein is actively removed from the T cell APC (antigen presenting cell) contact site suggesting a negative regulatory role in adaptive immune response.