CEA16 Polyclonal Antibody, 100ul Drying & Desiccation Several alternatively spliced transcript variants

Several alternatively spliced transcript variants have been found for CHEK1

Catalytic activity:ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine

Type I and II receptors form a stable complex after ligand binding

The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell

The protein encoded by SDC4 (syndecan 4) is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling

CEA16 Polyclonal Antibody, 100ul Drying & Desiccation Several alternatively spliced transcript variantsThe protein encoded by this gene is a secreted glycoprotein that in mouse interacts with tectorial membrane proteins in the inner ear. The encoded adhesion protein is found in cochlear outer hair cells and appears to be important for proper hearing over an extended frequency range. Defects in this gene likely are a cause of non syndromic autosomal dominant hearing loss.