ErbB-3 Polyclonal Antibody, 100ul[BT-AP03043] Lysosome Expression of this gene may

Expression of this gene may be downregulated in pancreatic cancer

This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias

This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis

suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells

subunit:Disulfide-linked heterodimer with the amino acid transport protein SLC3A2/4F2hc

ErbB-3 Polyclonal Antibody, 100ul[BT-AP03043] Lysosome Expression of this gene mayERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation