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RPA p32(Phospho Ser33) Polyclonal Antibody, 20ul In vitro Transcription the protein encoded by MMP14

SKU: 84156893178

4.5
PLN97.20 PLN141.20

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RPA p32(Phospho Ser33) Polyclonal Antibody, 20ul In vitro Transcription the protein encoded by MMP14Required for DNA recombination, repair and replication. The activity of RP A is mediated by single stranded DNA binding and protein interactions.,PTM: Phosphorylated in a cell cycle dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC DNA PK in the presence of Ku and DNA, and by CDC2.,subcellular location: Also present in PML

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Description

the protein encoded by MMP14 is a member of the membrane-type MMP (MT-MMP) subfamily

A similar protein in mouse plays a role in both interkinetic nuclear migration

Proteins of this subfamily| also referred to as alpha-CPs| bind to RNA with a specificity for C-rich pyrimidine regions

This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines

Alternative splicing has been observed at this locus and multiple variants

RPA p32(Phospho Ser33) Polyclonal Antibody, 20ul In vitro Transcription the protein encoded by MMP14Required for DNA recombination, repair and replication. The activity of RP A is mediated by single stranded DNA binding and protein interactions.,PTM: Phosphorylated in a cell cycle dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC DNA PK in the presence of Ku and DNA, and by CDC2.,subcellular location: Also present in PML

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