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Srb7 Polyclonal Antibody, 100ul DNA Synthesis |Associates with IL12B to form

SKU: 85054828335

4.6
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Srb7 Polyclonal Antibody, 100ul DNA Synthesis |Associates with IL12B to formMED21 (mediator complex subunit 21) encodes a member of the mediator complex subunit 21 family. The encoded protein interacts with the human RNA polymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes. A pseudogene of MED21 is located on chromosome 8. Alternative splicing results in multiple transcript variants.

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Description

|Associates with IL12B to form the IL-23 interleukin| an heterodimeric cytokine which functions in innate and adaptive immunity

with a resultant increased risk of myocardial infarction

Alternatively transcript variants encoding different isoforms have been described for this gene

consistent with the shared ACE2 predicted receptor (PMID: 32522207)

tissue specificity:Widely expressed with highest levels in the heart

Srb7 Polyclonal Antibody, 100ul DNA Synthesis |Associates with IL12B to formMED21 (mediator complex subunit 21) encodes a member of the mediator complex subunit 21 family. The encoded protein interacts with the human RNA polymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes. A pseudogene of MED21 is located on chromosome 8. Alternative splicing results in multiple transcript variants.

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