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PEA-15 Polyclonal Antibody, 50ul[BT-AP07045] Lysosome RARs are involved in various

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PEA-15 Polyclonal Antibody, 50ul[BT-AP07045] Lysosome RARs are involved in variousPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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Description

RARs are involved in various biological processes

resides in the critical region for VCFS/DGS on 22q11

and is considered to be an oncogene

Our adenoviral packaging system can accommodate large gene fragments and ensures high-level expression of target genes

The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity

PEA-15 Polyclonal Antibody, 50ul[BT-AP07045] Lysosome RARs are involved in variousPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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