RPGF4 Polyclonal Antibody, 50ul Mechanical Pipette In addition| this protein interacts

In addition| this protein interacts with BRCA1 and is phosphorylated by ATM| indicating a potential role for this protein in DNA repair

An important paralog of this gene is HLA-DMA

AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences

while the soluble form has only the catalytic domain

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RPGF4 Polyclonal Antibody, 50ul Mechanical Pipette In addition| this protein interactsThe DEP domain is involved in membrane localization independent from regulation by cAMP.,The N terminal nucleotide phosphate binding region cAMP 1 has a much lower affinity for cAMP as compared to cAMP 2.,Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP dependent, PKA independent exocytosis through interaction with RIMS2.,Contains 1 DEP