CD58 Polyclonal Antibody, 100ul[BT-AP01921] Micro Centrifuge Tubes Mediator complex subunit 17 encoded

Mediator complex subunit 17 encoded by MED17 is a subunit of the CRSP (cofactor required for SP1 activation) complex

Pseudogenes corresponding to MRPL49 (mitochondrial ribosomal protein L49)are found on chromosomes 5q and 8p

This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways

facilitating signal transduction

This gene is intronless and is expressed primarily in the frontal cortex of the brain

CD58 Polyclonal Antibody, 100ul[BT-AP01921] Micro Centrifuge Tubes Mediator complex subunit 17 encodedCFB (complement factor B) encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is