PAR-4 Polyclonal Antibody, 100ul Live Cell Imaging This protein is widely expressed

This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses

rather than by a transmembrane domain

This gene encodes the smallest subunit of dynactin| a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD

Functions cooperatively with CDC42 and Rac to generate additional structures

Upon activation by the cleavage of the activation peptide by thrombin and in the presence of calcium ion

PAR-4 Polyclonal Antibody, 100ul Live Cell Imaging This protein is widely expressedThis gene encodes a member of the protease activated receptor subfamily, part of the G protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients.