Amphiregulin Polyclonal Antibody, 50ul General Lab Use This enzyme is converted into

This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself

a circulating inhibitor of the formation of new blood vessels (angiogenesis)

Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage

Calcineurin like EF-hand protein 2 shares sequence similarity with calcineurin B and can bind to and stimulate the protein phosphatase activity of calcineurin A (CnA) and functions in the calcineurin/NFAT (nuclear factor of activated T cells) signaling pathway

a bleeding disorder (review by Lopez et al

Amphiregulin Polyclonal Antibody, 50ul General Lab Use This enzyme is converted intoThe amphiregulin encoded by AREG is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF alpha). The protein interacts with the EGF TGF alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell