UNC5B Polyclonal Antibody, 20ul Protein Research The protein encoded by this

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication

The human genome contains five CD1 family genes organized in a cluster on chromosome 1

Mutations in this gene have been associated with X-linked mental retardation

The axonemal dyneins| found in cilia and flagella| are components of the outer and inner dynein arms attached to the peripheral microtubule doublets

A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation

UNC5B Polyclonal Antibody, 20ul Protein Research The protein encoded by thisThis gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin 1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro and anti apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene.