GATA-4 Polyclonal Antibody, 100ul[BT-AP03485] Cell Screening and Imaging Transcript variants derived from alternative

Transcript variants derived from alternative splicing and/or alternative promoter usage exist

and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells

This gene has been found to be up-regulated in some human diseases

which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules

These isoforms exhibit different expression patterns and varying levels of GEF activity

GATA-4 Polyclonal Antibody, 100ul[BT-AP03485] Cell Screening and Imaging Transcript variants derived from alternativeGATA4 encodes a member of the GATA family of zinc finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. Transcription factor GATA 4 is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in GATA4 have been associated with cardiac septal defects. Additionally, alterations