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COG7 Rabbit Polyclonal Antibody, 100ul Modified Oligos The encoded protein also is

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COG7 Rabbit Polyclonal Antibody, 100ul Modified Oligos The encoded protein also isThe protein encoded by this gene resides in the golgi and constitutes one of the 8 subunits of the conserved oligomeric Golgi (COG) complex which is required for normal golgi morphology and localization. Mutations in this gene are associated with the congenital disorder of glycosylation type IIe.

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Description

The encoded protein also is required for the localization of some specific channels and can be part of a protein complex that couples synaptic vesicle exocytosis to cell adhesion in the brain

and the regulation of cell growth

The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex

Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE)

This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion| cell morphology and cell motility

COG7 Rabbit Polyclonal Antibody, 100ul Modified Oligos The encoded protein also isThe protein encoded by this gene resides in the golgi and constitutes one of the 8 subunits of the conserved oligomeric Golgi (COG) complex which is required for normal golgi morphology and localization. Mutations in this gene are associated with the congenital disorder of glycosylation type IIe.

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