Human Polycystin-1, PKD1 ELISA Kit , 96T Aspirating Pipets Contains 1 MIB/HERC2 domain

Contains 1 MIB/HERC2 domain

This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation (PubMed: 21436258)

Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3 (PubMed: 30580966)

It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions

It localizes to the outer membrane of mitochondria

Human Polycystin-1, PKD1 ELISA Kit , 96T Aspirating Pipets Contains 1 MIB/HERC2 domainComponent of a heteromeric calcium permeable ion Channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B (PubMed: 27214281). Both PKD1 and PKD2 are required for Channel activity (PubMed: 27214281). Involved in renal tubulogenesis (PubMed: 12482949). Involved in fluid flow mechanosensation by the primary cilium in renal epithelium (By similarity). Acts as a regulator of cilium