Bovine Insulin Like Growth Factor Binding Protein 3, IGFBP3 ELISA Kit, 96T Filtration Gene Ontology (GO) annotations related

Gene Ontology (GO) annotations related to this gene include poly(A) RNA binding and transcription factor binding

Some of its substrates include transforming growth factor beta related proteins| proalbumin| and von Willebrand factor

Observation of the histone nature of these subunits is supported by two types of evidence

EMR4P is a member of the EGF-TM7 receptor gene family which is thought to play a role in leukocyte adhesion and migration

The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation

Bovine Insulin Like Growth Factor Binding Protein 3, IGFBP3 ELISA Kit, 96T Filtration Gene Ontology (GO) annotations relatedIGF binding proteins prolong the half life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF independent antiproliferative and apoptotic effects mediated by its receptor TMEM219 IGFBP 3R.