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Shc Polyclonal Antibody, 100ul[BT-AP08290] Purification Hard and wear-resistant PP

SKU: 95327483222

4.9
USD123.75 USD155.75

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Shc Polyclonal Antibody, 100ul[BT-AP08290] Purification Hard and wear-resistant PPSHC1 encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation. Unlike the

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Description

Hard and wear-resistant PP

cortactin is degraded in a caspase-dependent manner

whereas A2 is specifically expressed in the testis

Transcript variants utilizing alternative polyA signals and alternative 5'-terminal exons exist but all encode the same protein

The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta

Shc Polyclonal Antibody, 100ul[BT-AP08290] Purification Hard and wear-resistant PPSHC1 encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation. Unlike the

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