E2F-6 Polyclonal Antibody, 20ul Drying & Desiccation May play a pivotal role

May play a pivotal role in the formation and/or maintenance of lipid rafts

The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling

The protein has substantial GAP activity towards several Rho-family GTPases in vitro

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It localizes to both the nucleus and the cytoplasm

E2F-6 Polyclonal Antibody, 20ul Drying & Desiccation May play a pivotal roleE2F6 encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. E2F transcription factor 6 encoded by E2F6 lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene