DCK Rabbit Polyclonal Antibody, 50ul Thermo Mix RIO-type Ser/Thr kinase family

RIO-type Ser/Thr kinase family

The human genome contains several non-transcribed pseudogenes related to this gene

Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II)

as well as other neuronal ceroid-lipofuscinosis (CLN) genes

Marfan Syndrome

DCK Rabbit Polyclonal Antibody, 50ul Thermo Mix RIO-type Ser/Thr kinase familyDeoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug