MYO3B Polyclonal Antibody, 50ul Mini dry bath Interaction with PDCD1 inhibits T-cell

Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production

Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma

The human HUNK gene localizes to chromosome 21q22 and encodes a protein with nucleocytoplasmic distribution and localizes to the centrosome

Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease

subcellular location:Also present in PML nuclear bodies

MYO3B Polyclonal Antibody, 50ul Mini dry bath Interaction with PDCD1 inhibits T-cellThis gene encodes one of the class III myosins. Myosins are ATPases, activated by actin, that move along actin filaments in the cell. This class of myosins are characterized by an amino terminal kinase domain and shown to be present in photoreceptors. Alternative splicing results in multiple transcript variants encoding different isoforms.