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Factor I Polyclonal Antibody, 100ul Cryogenic Vials It is mitogenic for fibroblasts

SKU: 96523918408

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Factor I Polyclonal Antibody, 100ul Cryogenic Vials It is mitogenic for fibroblastsCFI encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an

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Description

It is mitogenic for fibroblasts and smooth muscle but not endothelial cells

Also in fetal lung fibroblasts and fetal brain

The protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix

and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms

The beta-1

Factor I Polyclonal Antibody, 100ul Cryogenic Vials It is mitogenic for fibroblastsCFI encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an

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