FAK(Phospho Ser843) Polyclonal Antibody, 50ul Reservoirs It stabilizes APP and inhibits

It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients

The protein shares strong similarity with a Drosophila protein which interacts with the transcription factor disco and is expressed in the nervous system

subunit:Binds EEA1

MAP2K4 encodes a member of the mitogen-activated protein kinase (MAPK) family

This protein may function in stimulation of Ca2+-induced Ca2+ release

FAK(Phospho Ser843) Polyclonal Antibody, 50ul Reservoirs It stabilizes APP and inhibitsThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal