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p53(Phospho Thr387) Polyclonal Antibody, 50ul Liquid Handling Binding to the H1F0 promoter

SKU: 97763842156

4.0
USD162.00 USD189.00

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p53(Phospho Thr387) Polyclonal Antibody, 50ul Liquid Handling Binding to the H1F0 promoterThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

Binding to the H1F0 promoter is enhanced by interaction with RB1

West Nile virus (WNV)

The encoded protein also functions in mitochondrial DNA replication and repair

Mutations in CSH1 result in placental lactogen deficiency and Silver-Russell syndrome

The encoded protein is part of a complex that responds to beta-adrenergic signals by inhibiting adenylate cyclase

p53(Phospho Thr387) Polyclonal Antibody, 50ul Liquid Handling Binding to the H1F0 promoterThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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