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GHR Polyclonal Antibody, 50ul Apoptosis & Autophagy This gene encodes a very

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GHR Polyclonal Antibody, 50ul Apoptosis & Autophagy This gene encodes a veryGHR encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature.

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Description

This gene encodes a very large RAN-binding protein that immunolocalizes to the nuclear pore complex

INCENP (inner centromere protein) and survivin

Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency

It probably plays a role in the regulation of acute-phase reaction| inflammation and hemopoiesis

This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains

GHR Polyclonal Antibody, 50ul Apoptosis & Autophagy This gene encodes a veryGHR encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature.

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