TOPRS Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) 2000 [PubMed 10888605])

2000 [PubMed 10888605])

including breast cancer and possibly Alzheimer's disease

Belongs to the cation transport ATPase (P-type) family

ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences

but is not expressed in differentiated cells

TOPRS Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) 2000 [PubMed 10888605])This gene encodes a nuclear protein which is serine and arginine rich, and contains a RING type zinc finger domain. It is highly expressed in the testis, and functions as an ubiquitin protein E3 ligase. Mutations in this gene are associated with retinitis pigmentosa type 31. Alternatively spliced transcript variants, encoding different isoforms, have been observed for this locus.