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CD2AP Polyclonal Antibody, 20ul Microbial Genome Editing SLP-76 also contains a central

SKU: 99407589412

4.3
PLN97.20 PLN117.20

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CD2AP Polyclonal Antibody, 20ul Microbial Genome Editing SLP-76 also contains a centralThis gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane

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Description

SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain

while the expression of Dbf4 is absent during G1 phase and accumulates during S and G2 phases

The protein encoded by this gene is the fifth subunit of GPI transamidase that attaches GPI-anchors to proteins

and has been shown to regulate the helicase activity of the complex

Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation

CD2AP Polyclonal Antibody, 20ul Microbial Genome Editing SLP-76 also contains a centralThis gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane

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