Vav(Phospho Tyr174) Polyclonal Antibody, 50ul Oligo Pool CENPA encodes a centromere protein

CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere

In response to TGF-beta signal

|Contains 1 Gla (gamma-carboxy-glutamate) domain

and its expression is inducible by serum

The encoded protein may also play a role in synaptic maturation during cortical development

Vav(Phospho Tyr174) Polyclonal Antibody, 50ul Oligo Pool CENPA encodes a centromere proteinThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.