IRF-5 Polyclonal Antibody, 20ul Cryogenic Vials The adenovirus E1A protein both

The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation

which further interacts with the other family members

is essential for nucleotide synthesis by salvage pathways in cells that lack de novo biosynthetic pathways

this interaction prevents nuclear translocation and DNA-binding

is a multifunctional protein that is essential for maintaining erythrocyte shape and membrane mechanical properties

IRF-5 Polyclonal Antibody, 20ul Cryogenic Vials The adenovirus E1A protein bothThis gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N terminal DNA binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have