DOC11 Polyclonal Antibody, 100ul Cell Culture Within the sequence used as

Within the sequence used as an immunogen

Members of this family are characterized by long N-termini and multiple functional domains

thereby negatively regulating the activity of the DDX58 gene product

The protein lacks the cytoplasmic domain characteristic of other cadherins

This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2| and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1| MAP3K2/MEKK2|MAP3K3/MEKK5| and MAP4K2/GCK

DOC11 Polyclonal Antibody, 100ul Cell Culture Within the sequence used asThe DHR 2 domain is necessary for the GEF activity.,Guanine nucleotide exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP.,miscellaneous:'Zizim' means 'spike' in Hebrew.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the DOCK family.,Contains 1 DHR 1 (CZH 1) domain.,Contains 1 DHR 2 (CZH 2) domain.,Contains 1 PH domain.,subunit: Interacts with CDC42.,