VU 0240551 Catalog No.:M8631-10 EW-7197 HCl

EW-7197 HCl

Krishnaiah M

It may represent a good lead compound for a subset of Parkinson's disease

is a potent inhibitor of β-catenin-responsive transcription (CRT) that inhibits Wnt signaling in a reporter assay in vitro (IC50 = 40

InChiKey: GJJFMKBJSRMPLA-HIFRSBDPSA-N

VU 0240551 Catalog No.:M8631-10 EW-7197 HClVU0240551 is an inhibitor of the neuronal K Cl cotransporter, KCC2 (IC50 = 560 nM for K+ uptake assay in KCC2 overexpressing cells). VU0240551 exhibits selectivity over the Na K 2Cl cotransporter, NKCCl. It also inhibits hERG and L type Ca2+ channels. Product information CAS Number: 893990 34 6 Molecular Weight: 342. 44 Formula: C16H14N4OS2 Synonym: VU0240551 VU 0240551 Chemical Name: N (4 methyl 1,3 thiazol 2 yl) 2 [(6 phenylpyridazin 3