BLU-554 - CAS# 1707289-21-1. CAS# 1707289-21-1 284 Molecular Weight: 406

Molecular Weight: 406

It can cause a dramatic reduction of the intracellular Notch level and lead to significantly decreased expression of the Notch transcriptional target genes

Stem Cell Reports

Patterson JW

Treatment with DMH1 reduced lung metastasis and the tumors were less proliferative and more apoptotic

BLU-554 - CAS# 1707289-21-1. CAS# 1707289-21-1 284 Molecular Weight: 406BLU 554, also known as Fisogatinib, CAS No. 1707289 21 1, CAS No. 1707289 21 1, is a fibroblast growth factor receptor 4 (FGFR4) inhibitor potentially for the treatment of hepatocellular carcinoma and cholangiocarcinoma. BLU 554 demonstrates clinical benefit and tumor regression in patients with HCC with aberrant FGF19 expression. Product information CAS Number: 1707289 21 1 Molecular Weight: 503. 38 Formula: C24H24Cl2N4O4 Synonym: BLU 554 Fisogatinib