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AMG-208 - CAS# 1002304-34-8 K-4827 Tosylate 18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20

AMG-208 - CAS# 1002304-34-8 K-4827 Tosylate 18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20

Name: AMG-208 - CAS# 1002304-34-8 K-4827 Tosylate 18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20
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SKU: 39743103760
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AMG-208 - CAS# 1002304-34-8 K-4827 Tosylate 18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20AMG 208 is a selective small molecule inhibitor of the proto oncogene c Met with potential antineoplastic activity. c Met inhibitor AMG 208 inhibits the ligand dependent and ligand independent activation of c Met, inhibiting its tyrosine kinase activity, which may result in cell growth inhibition in tumors that overexpress c Met. C Met encodes the hepatocyte growth factor receptor tyrosine kinase, plays an important role in epithelial cell

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Description

18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20

Formula: C27H28N4O3S2

PubMed PMID: 23991670

InChiKey: GEZHEQNLKAOMCA-RRZNCOCZSA-N

ClH/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19

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