OTSSP167 - CAS# 1431697-89-0 Catalog No.:M9991-10 Hernandez D

Hernandez D

Chemical Name: A name could not be generated for this structure

[Epub ahead of print] PubMed PMID: 27989726

Peräniemi S

Chemical Name: N-(4-(benzyloxy)-3-methoxybenzyl)-5-phenyl-N-(2-(pyridin-2-yl)ethyl)pentanamide

OTSSP167 - CAS# 1431697-89-0 Catalog No.:M9991-10 Hernandez DOTSSP167, also known as OTS167, is an orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity. Upon administration, OTS167 binds to MELK, which prevents both MELK phosphorylation and activation; thus inhibiting the phosphorylation of downstream MELK substrates. This may lead to an inhibition of both cell proliferation and survival in MELK expressing tumor cells. Product information CAS