Lenvatinib - CAS# 417716-92-8 K474 The inhibitory effect of Staurosporine

The inhibitory effect of Staurosporine is statistically significant at around Wk 10 of tumor promotion

2013 Jun 13

InChi: InChI=1S/2C21H29N6O5P

PubMed Central PMCID: PMC5838759

PF-06282999 is moderately bound to plasma proteins across preclinical species and humans

Lenvatinib - CAS# 417716-92-8 K474 The inhibitory effect of StaurosporineLenvatinib, also known as E7080, is a synthetic, orally available inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR FLK 1) tyrosine kinase with potential antineoplastic activity. E7080 blocks VEGFR2 activation by VEGF, resulting in inhibition of the VEGF receptor signal transduction pathway, decreased vascular endothelial cell migration and proliferation, and vascular endothelial cell apoptosis. Product information