Signal · Product Feed

Crizotinib Hydrochloride - CAS# 1415560-69-8 Catalog No.:M10974-2 InChi: InChI=1S/C24H25FN6O/c1-29(23-26-13-10-22(32)28-23)19-11-14-30(15-12-19)24-27-20-4-2-3-5-21(20)31(24)16-17-6-8-18(25)9-7-17/h2-10

Crizotinib Hydrochloride - CAS# 1415560-69-8 Catalog No.:M10974-2 InChi: InChI=1S/C24H25FN6O/c1-29(23-26-13-10-22(32)28-23)19-11-14-30(15-12-19)24-27-20-4-2-3-5-21(20)31(24)16-17-6-8-18(25)9-7-17/h2-10

Name: Crizotinib Hydrochloride - CAS# 1415560-69-8 Catalog No.:M10974-2 InChi: InChI=1S/C24H25FN6O/c1-29(23-26-13-10-22(32)28-23)19-11-14-30(15-12-19)24-27-20-4-2-3-5-21(20)31(24)16-17-6-8-18(25)9-7-17/h2-10
Brand: dianalocatelli.com
SKU: 6384587363
Price: 140.30 USD
Availability: InStock
Rating: 4.5517 (10 reviews)

SKU: 6384587363

4.6

USD140.30 USD179.30

Pay in 4 interest-free payments of $35.08 Learn more

Shipping Estimate
USA

USA

CAN

Ships within 48 hours · Estimated delivery Aug 13 - Aug 18

Live Spec

Crizotinib Hydrochloride - CAS# 1415560-69-8 Catalog No.:M10974-2 InChi: InChI=1S/C24H25FN6O/c1-29(23-26-13-10-22(32)28-23)19-11-14-30(15-12-19)24-27-20-4-2-3-5-21(20)31(24)16-17-6-8-18(25)9-7-17/h2-10Crizotinib (PF 02341066) hydrochloride (Xalkori) inhibits tyrosine phosphorylation of c Met and nucleophosmin (NPM) anaplastic lymphoma kinase (ALK) with IC50 of of 11 nM and 24 nM in cell based assays, respectively. Crizotinib hydrochloride is also a potent ROS1 inhibitor with Ki less than 0. 025 nM. Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines. Product information CAS Number: 1415560 69 8

Store: dianalocatelli.com · Domain: dianalocatelli.com

Description

InChi: InChI=1S/C24H25FN6O/c1-29(23-26-13-10-22(32)28-23)19-11-14-30(15-12-19)24-27-20-4-2-3-5-21(20)31(24)16-17-6-8-18(25)9-7-17/h2-10

45 Suppl 4

at concentrations between 0

Orexin antagonists have multiple potential clinical applications including the treatment of drug addiction

Formula: C21H19ClN4O4

Exchange/Return Notes