Zibotentan (ZD4054) pristin 36-27(34)19-35-4)15-17-33(3)16-7-10-26-31-24-8-5-6-9-25(24)32-26

36-27(34)19-35-4)15-17-33(3)16-7-10-26-31-24-8-5-6-9-25(24)32-26

InChiKey: HUFOZJXAKZVRNJ-UHFFFAOYSA-N

delays in vitro HbS polymerization and prevents sickling of red blood cells (RBCs)

5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]phenyl)phenoxy]butoxy]acetamido)-3

949912-58-7

Zibotentan (ZD4054) pristin 36-27(34)19-35-4)15-17-33(3)16-7-10-26-31-24-8-5-6-9-25(24)32-26An orally available selective antagonist of the endothelin A (ET A) receptor with potential antineoplastic activity. Zibotentan binds selectively to the ET A receptor, thereby inhibiting endothelin mediated mechanisms that promote tumor cell proliferation. Product information CAS Number: 186497 07 4 Molecular Weight: 424. 43 Formula: C19H16N6O4S Chemical Name: 2 (4 (1, 3, 4 oxadiazol 2 yl)phenyl) N (3 methoxy 5 methylpyrazin 2 yl)pyridine 3