SD70 - Histone Demethylase JMJD2 Inhibitor. CAS# 332173-89-4 6057 Chemical Name: Compound Library of

Chemical Name: Compound Library of Histone Demethylase

InChiKey: ZKXZLIFRWWKZRY-KRWDZBQOSA-N

SGC0946 was delivered via subcutaneously implanted mini-osmotic pumps capable of continuous infusion (drug load is ~50 mg/ml solution) for a period of 7 days in animal models

(2016) Nature

Molecular Weight: 462

SD70 - Histone Demethylase JMJD2 Inhibitor. CAS# 332173-89-4 6057 Chemical Name: Compound Library ofSD70, CAS No. 332173 89 4, is a potent, selective and cell permeable inhibitor of histone demethylase JMJD2 (KDM4C), identified by phenotypic screening for inhibitors of ligand and genotoxic stress induced translocations in prostate cancer cells. Through Chem seq approach, SD70 was found to inhibit the androgen dependent AR program and prostate cancer cell growth, acting, at least in part, by functionally inhibiting the Jumonji domain containing