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XL413 e F Treatment with Abiraterone significantly inhibited

XL413 e F Treatment with Abiraterone significantly inhibited

Name: XL413 e F Treatment with Abiraterone significantly inhibited
Brand: dianalocatelli.com
SKU: 75253452258
Price: 108.00 USD
Availability: InStock
Rating: 4.6039 (6 reviews)

SKU: 75253452258

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XL413 e F Treatment with Abiraterone significantly inhibitedBMS 863233, also known as XL 413, is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. CDC7 kinase inhibitor BMS 863233 binds to and inhibits the activity of CDC7, which may result in the inhibition of DNA replication and mitosis, the induction of tumor cell apoptosis, and the inhibition of tumor cell proliferation in CDC7 overexpressing tumor cells. CDC7, a serine threonine kinase

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Description

Treatment with Abiraterone significantly inhibited CRPC progression in the robustly growing subset

0000000000000685

CAS Number: 154-23-4

induces apoptosis

In mouse xenograft models of Bel-7402

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