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TBB - CAS# 17374-26-4 60116 TH-302 is currently in a

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TBB - CAS# 17374-26-4 60116 TH-302 is currently in aTBB, CAS No. 17374 26 4, is a potent protein kinase CK2 inhibitor, which induces apoptosis and caspase dependent degradation of haematopoietic lineage cell specific protein 1 (HS1) in Jurkat cells. Product information CAS Number: 17374 26 4 Molecular Weight: 434. 71 Formula: C6HBr4N3 Synonym: TBB NSC 231634 NSC231634 Tetrabromobenzotriazole NSC 231634 Chemical Name: 4,5,6,7 tetrabromo 1H benzo[d][1,2,3]triazole Smiles: BrC1C2N=NNC=2C(Br)=C(Br)C=1Br

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Description

TH-302 is currently in a phase II clinical trial for the treatment of soft tissue sarcoma

000-fold reduction in luminescence signal

120(13):2016-24

Rodriguez MA

HCT116 cells are pre-treated with the PTEN inhibitor SF-1670 (2 μM) for 24 h (untreated HCT116 cells served as control)

TBB - CAS# 17374-26-4 60116 TH-302 is currently in aTBB, CAS No. 17374 26 4, is a potent protein kinase CK2 inhibitor, which induces apoptosis and caspase dependent degradation of haematopoietic lineage cell specific protein 1 (HS1) in Jurkat cells. Product information CAS Number: 17374 26 4 Molecular Weight: 434. 71 Formula: C6HBr4N3 Synonym: TBB NSC 231634 NSC231634 Tetrabromobenzotriazole NSC 231634 Chemical Name: 4,5,6,7 tetrabromo 1H benzo[d][1,2,3]triazole Smiles: BrC1C2N=NNC=2C(Br)=C(Br)C=1Br

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