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PF-06282999 - CAS# 1435467-37-0 size:2mg solid Smiles: CCCN1C(NC(=O)C2=CC(=CC=C2)C(N)=O)=NC2=CC=CC=C12

PF-06282999 - CAS# 1435467-37-0 size:2mg solid Smiles: CCCN1C(NC(=O)C2=CC(=CC=C2)C(N)=O)=NC2=CC=CC=C12

Name: PF-06282999 - CAS# 1435467-37-0 size:2mg solid Smiles: CCCN1C(NC(=O)C2=CC(=CC=C2)C(N)=O)=NC2=CC=CC=C12
Brand: dianalocatelli.com
SKU: 97919743671
Price: 48.00 USD
Availability: InStock
Rating: 4.4257 (5 reviews)

SKU: 97919743671

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PF-06282999 - CAS# 1435467-37-0 size:2mg solid Smiles: CCCN1C(NC(=O)C2=CC(=CC=C2)C(N)=O)=NC2=CC=CC=C12PF 06282999, CAS No. 1435467 37 0, is a potent and selective myeloperoxidase Inhibitor which is potential useful for the Treatment of Cardiovascular Diseases. PF 06282999 displayed excellent oral pharmacokinetics in preclinical species and robust irreversible inhibition of plasma MPO activity both in human blood stimulated exogenously and in plasma collected after oral (po) administration to lipopolysaccharide (LPS) treated cynomolgus monkeys. PF

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Description

Smiles: CCCN1C(NC(=O)C2=CC(=CC=C2)C(N)=O)=NC2=CC=CC=C12

Formula: C28H30F3N7O3

51(12):946-51

Upon treatment with higher concentrations of Tacrolimus (100-1

Smiles: COC1C(=CC=CC=1C1=NC2=CC=C3NN=CC3=C2C2CCCC=21)B(O)O

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